Tumor microenvironment and the role of autophagy in hypoxic tumors

Organizer Karolinska Institutet in collaboration with Sprint Bioscience
Time 2017-10-13 09:00
Location Wallenbergsalen, Nobel Forum, Nobels väg 1, Stockholm
Booking for mini-symposium
 

PROGRAM & SPEAKERS:

Chaired by Katja Pokrovskaja Tamm and Angelo De Milito 


09:00 – 09:10 Lars Holmgren, Vice Chair Dep. Oncology-Pathology, Karolinska Intitutet, Jessica Martinsson, Sprint Bioscience
Welcome

09:10 – 09:30 Anders Lönnberg, Swedish Government, National Coordinator for Life Science


09:30 – 10:00 Ravi Amaravadi, University of Pennsylvania, Philadelphia
Targeting the lysosome in the tumor microenvironment


10:00 – 10:30 Bassam Janji, Luxembourg Institute of Health, Luxemburg
Impact of targeting autophagy on the immune landscape of melanoma


10:30 – 11:00 Randall Johnson, Karolinska Institutet
The role of hypoxia in cytotoxic T cell immunotherapy


11:00 – 11:30 Coffee break with sandwich/pastry


11:30 – 11:45 Yasmin Yu, Karolinska Institutet - Sprint Bioscience
Development of selective Vps34 inhibitors to modulate autophagy in tumors


11:45 – 12:00 Matheus Dyczynski, Karolinska Institutet
Targeting Vps34 improves chemosensitivity of triple negative breast cancer cells


12:00 – 12:30 Michail Sitkovsky, Northeastern University, Boston
Anti-Hypoxia/HIF-1alpha and anti-A2A-Adenosinergic Co-adjuvants to enable the rejection of the most therapy-resistant tumors


12:30 – 13:00 Pär Nordlund, Karolinska Institutet
Protein biophysics to dissect cellular responses to cancer drugs


13:00 Concluding remarks